Medi-Cal and GLP-1s
California wrote this one into the state budget and then executed it through the pharmacy benefit. Since January 1, 2026, Medi-Cal Rx claims for Wegovy, Zepbound and Saxenda reject at the counter. Two exceptions survived, and one of them opened up in April.
What changed, and what the document says
Wegovy, Zepbound, Saxenda
Not coveredOff the Contract Drugs List since January 1, 2026. Approvals already granted expired the day before.
“Claims for these three drugs will deny with Reject Code 70 – Product/ Service Not Covered regardless of indication, and previously approved prior authorizations (PAs) are deemed expired.”
Medi-Cal Rx, California Department of Health Care Services (DHCS) — January 1, 2026
Zepbound for sleep apnea
Conditions applyThe one surviving route to Zepbound. Prior authorization, case by case, for obstructive sleep apnea.
“PA requests for Zepbound will be considered when used for obstructive sleep apnea (OSA).”
Medi-Cal Rx, California Department of Health Care Services (DHCS) — December 12, 2025; Last Updated April 6, 2026
Wegovy for liver disease
CoveredOpened up in April 2026, and it doesn't need prior authorization — but the claim has to carry the right diagnosis code or it rejects.
“Effective April 1, 2026, Wegovy does not require an approved prior authorization (PA) when prescribed for the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH).”
Medi-Cal Rx, California Department of Health Care Services (DHCS) — December 12, 2025; Last Updated April 6, 2026
Ozempic, Mounjaro and the rest
ContextSeven other GLP-1s stayed on the list, locked to a type 2 diabetes diagnosis. None of them is a route to a weight-loss prescription.
“The following GLP-1 drugs are currently on the CDL and continue to have a Code I diagnosis restriction of type 2 diabetes.”
Medi-Cal Rx, California Department of Health Care Services (DHCS) — December 12, 2025; Last Updated April 6, 2026
Under 21
CoveredA federal children's benefit still forces a medical-necessity review, even for weight loss.
“Effective January 1, 2026, PA requests submitted for weight loss or weight loss-related indications will be reviewed for medical necessity for members younger than 21 years of age pursuant to the federal Early and Periodic Screening, Diagnostic, and Treatment (EPSDT) benefit.”
Medi-Cal Rx, California Department of Health Care Services (DHCS) — December 12, 2025; Last Updated April 6, 2026
Where it came from
ContextThe enacted state budget, as a line item under pharmacy savings.
“Specialty Drug Coverage for Weight Loss—Elimination of coverage for Glucagon-Like Peptide-1 (GLP-1) drugs for weight loss effective January 1, 2026.”
State of California, Gavin Newsom, Governor — 2025-26
Telehealth in California
- Enhance MDPartnerBMinor gap$99 a monthSee Enhance MD pricing (opens in a new tab)
- TrimiPartnerBMinor gap$175 a monthSee Trimi pricing (opens in a new tab)
- Gala HealthPartnerCCaveat$179 a monthSee Gala Health pricing (opens in a new tab)
Some providers pay us a commission when you sign up through our links, at no extra cost to you.
Which of these companies serve California?
Of the 284 companies we grade, 28 publish a list of the states they are licensed in. We checked 250 more and found no such list on any page we read; 6 we have not checked either way.
20 of those lists name California: Gala Health, Care Bare Rx, Vita Bella, TelePeptide, Invyncible, JumpstartMD, Wisp, WePeptideRx, Ways2Well, Tyde Wellness, Willow, VevaRx, Trimi, Enhance MD, HumeCare+, Rx.com, Mojoon, Peak Wellness, Allara Health, and MEDvidi. That is a licensure claim each company makes about itself, not something we checked with a state board.
A published list is a starting point, not a guarantee. If availability decides your choice, ask before you pay and get the answer in writing.
Coverage decides what you pay before cash does. See how state Medicaid programs cover GLP-1s and what a prior-authorization denial turns on.
Sources
Each document below was fetched and read on the date shown beside it, which is the date printed on the document — not always the date in its web address. All of them were read in September 2026.
- Changes to Medi-Cal Rx, Effective January 1, 2026 — Medi-Cal Rx, California Department of Health Care Services (DHCS). printed under the title on page one: January 1, 2026.
- GLP-1 Coverage Considerations — Medi-Cal Rx, California Department of Health Care Services (DHCS). printed on the document's second line — the URL path reads 2025/12, four months behind the paper: December 12, 2025; Last Updated April 6, 2026.
- California State Budget 2025-26 — State of California, Gavin Newsom, Governor. the fiscal year on the cover — this document prints no publication date, so none is supplied here: 2025-26.
Nothing on this page is medical advice, and nobody here is a clinician. Coverage rules change; check the linked document before you rely on it.
If you're paying cash instead
These providers list California in their service area. Partners appear first. These are medication prices, not confirmed monthly totals. Other fees may apply; check each provider’s terms before choosing.
Some providers pay us a commission when you sign up through our links, at no extra cost to you.
| Provider | Monthly price and terms | Go to the provider |
|---|---|---|
Enhance MDBMinor gap | $99Signup price a month, medication onlycompounded NAD+ sublingual wafers, month to monthBehind the NAD+ Wafers tab on the same page. The 1-month plan, billed every four weeks; $84 is the 12-month rate.Additional fees not verified.Price details
| View pricing at Enhance MD (opens in a new tab)Partner |
TrimiBMinor gap | $175 a month, medication onlycompounded semaglutide, billed monthlyMonth to month. $99 is the twelve-month rate, billed $1,188 upfront, and it's the only semaglutide figure on the homepage. Medication, supplies, provider access and shipping included. Monthly renewal is automatic; payment precedes provider review.Additional fees not verified.Price details
| View pricing at Trimi (opens in a new tab)Partner |
Gala HealthCCaveat | $179 a month, medication onlycompounded semaglutideThe product page states a yearly subscription. The homepage FAQ quotes $199 a month on a three-month plan, while the weight-loss overview advertises semaglutide from $129 without a term. A single-month price is not established.Additional fees not verified.Price details
| View pricing at Gala Health (opens in a new tab)Partner |
HumeCare+CCaveat | $199Signup price a month, medication onlycompounded semaglutide, annual plan$169 the first month, $199 a month after, $2,358 for the year, payable in up to 12 installments, per the checkout.Additional fees not verified.Price details
| View pricing at HumeCare+ (opens in a new tab)Partner |
WillowCCaveat | $299 a month, medication onlycompounded semaglutide injectionPrinted on the product page with no asterisk and no dose qualifier. The comparison page and the terms both add one.Additional fees not verified.Price details
| View pricing at Willow (opens in a new tab)Partner |
TelePeptideAVerified | $99 a month, medication onlycompounded sermorelinThe annual tier for the same sermorelin program, billed $1,188 upfront. It is the cheapest sermorelin rate on the chart and it requires a year.Additional fees not verified.Price details
| View pricing at TelePeptide (opens in a new tab) |
Care Bare RxBMinor gap | $199 a month, medication onlycompounded semaglutideNo plan term is attached to this figure anywhere we read it, which is unusual in this market. Care Bare Rx's own FAQ does say price varies by dose, so treat $199 as a floor rather than a fixed monthly charge.Additional fees not verified.Price details
| View pricing at Care Bare Rx (opens in a new tab) |
MEDvidiBMinor gap | No verified month-to-month medication price.Charged per visit rather than every month, so it is not in the figure above: $195 for weight loss introductory consultation, $159 for weight loss follow-up consultation, $249 for introductory and follow-up consultation package.See the review for plan prices and full terms. | View pricing at MEDvidi (opens in a new tab) |
Our grading method and how we verify a price explain what those letters mean and where these figures came from.